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According to CMS guidance, physicians who prescribe GLP-1 drugs under the Bridge must attest to the patient's clinical eligibility at the time therapy was first initiated even if that initial prescription was written before July 1, 2026
Retatrutide is studied as a triple agonist because it includes GLP-1, GIP and glucagon receptor activity
Direct head-to-head trials are not yet available, but comparing across studies suggests retatrutide produces approximately 6-10 percentage points more weight loss than tirzepatide at equivalent treatment durations
If nausea from semaglutide makes drinking difficult, consider small, frequent sips of clear broths, herbal teas, and electrolyte solutions rather than trying to drink large glasses of water
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