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EOD dosing appears sufficient for anti-aging goals where the downstream gene expression changes outlast the peptide's plasma clearance GHK-Cu's impact on collagen and elastin gene expression persists for days after a single dose, meaning you don't necessarily need daily systemic presence

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This positions GHK-Cu as a model substrate for studying small-peptide control of large gene-network programs.[9] Redox-Silenced Copper Delivery Studies Bioinorganic chemistry investigations use GHK-Cu as a model carrier for delivering Cu(II) to cells without triggering Fenton-driven hydroxyl-radical generation