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Mechanistically, it only has one vector for weight loss
doi: 10.1007/s00125-022-05715-4 131 Snchez-GarridoMABrandtSJClemmensenCMllerTDDiMarchiRDTschpMHet al
With the current absence of technologies to rectify the actual mutations that underlie mitochondrial diseases, medical science can only address the resulting oxidative stress as a potential therapeutic option
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This translated into a significantly higher likelihood of achieving the conventional glycemic target of HbA1c 30, those randomized to tirzepatide experienced 36 adjudicated cardiovascular deaths or heart failure worsening events versus 56 in the placebo group, representing a 38% reduction primarily driven by fewer heart failure exacerbations
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