The comparison of their accumulation patterns in resistance, susceptible, and mock responses revealed a marked GST accumulation during resistance responses pointing to the role of GST as a positive regulator of resistance (Bai et al., External factors, such as light have a strong influence on plant defense reactions and disease resistance

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This highlights the complexity of GPCR activation, where downstream signalling is influenced by the interplay of multiple transducers that can interact with activated receptors (pleiotropic coupling), and can also be influenced by different trafficking profiles that alter the location of the receptor in the cell
For instance, ozone exposure or enhanced intracellular H 2 O 2 can drive high accumulation of glutathione (Bick et al., 2001