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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. Study Data The study authors used the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA between January 1, 2018, and January 1, 2023

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