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The group of GPx enzymes, which play an irreplaceable role in the regulation of ROS homeostasis in vivo, has been thought to use GSH as a reducing agent to catalyze the reduction of H 2 O 2 or organic peroxides to generate water or corresponding alcohols, respectively [17]
Overdose may cause severe nausea, vomiting, or low blood sugar
Long viewed as obesity and diabetes drugs with incidental renal benefits, GLP-1s are now discussed as emerging tools for type 2 diabetes (T2D) associated chronic kidney disease (CKD) management
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