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These findings indicate that phenobarbital and trans-stilbene oxide both induce epoxide hydrolase non-uniformly within the hepatic lobule

An entirely new research program: characterization of the blends stability and pharmacokinetics, controlled animal studies of the combination with appropriate endpoints, factorial experiments to test for genuine synergy, and eventually adequately powered, randomized, placebo-controlled human trials with predefined outcomes and safety monitoring conducted under regulatory oversight

Oxidative stress becomes problematic if it goes unchecked, because it can damage tissue, important proteins, and even cell DNA

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