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Interestingly, the neural inhibitory effect is linked to reduced expression of voltage-gated sodium channel 1.6 (Nav1.6) in glutamatergic neurons following pilocarpine-induced SE [30]
Keep a symptom diary when starting supplementation and be particularly alert for signs of allergic reactions
They are also responsible for the development of male secondary sexual characteristics (androgenic effect) ( Uncontrolled use of substances from the AAS group for non-medical purposes is associated with a high risk of adverse effects on the liver and the reproductive, musculoskeletal, cardiovascular, and central nervous systems
This question makes it so important to determine the pathway(s) for glutamate degradation not only in isolated astrocytes but also in intact brain tissue (see papers by McKenna and by Whitelaw and Robinson in this Research Topic)
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