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By regulating the pool of available actin monomers, TB4 and by extension the TB-500 fragment is thought to enhance the ability of cells such as endothelial cells, keratinocytes, and fibroblasts to migrate toward and repopulate a wound

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FIGURE 7 Discussion In this study, a high concentration cholesterol-induced lipotoxicity was observed in INS-1 cells, including inhibited cell viability, enhanced cell apoptosis, and inhibited cholesterol efflux from INS-1 cells