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Figure 7 Placebo-Controlled Studies With DPP-4 Inhibition as Add-on to Ongoing Metformin Therapy The DPP-4 inhibitors were also examined as add-on to on-going metformin in subjects with type 2 diabetes in 2426 week studies with a total number of 3,216 subjects [Table 2

Whether adding cagrilintide preserves more lean mass than retatrutide alone or whether the added satiety drives more lean-mass loss by reducing protein intake further is unknown