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Conversely, HIF-1 overexpression significantly upregulated the expression of these proteins

By encouraging the repair of damaged cartilage, it aids in restoring joint mobility and reducing wear and tear (8)

By Sidra Healthcare Team | Reviewed by a DHA-Licensed GP | Updated: April 2026 Healthy and glowing skin is a priority for many people in Dubai , where environmental factors such as heat, pollution, and sun exposure can affect skin health

52,53 In a phase 2, multi-center trial conducted at 45 centers, orforglipron at doses of 12 mg or greater showed significant reductions in HbA1c and bodyweight compared with placebo or dulaglutide