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In the landmark study that introduced it, published in Cell Metabolism (Lee et al., 2015), researchers showed that MOTS-c regulates insulin sensitivity and metabolic homeostasis through the AMPK pathway, and that treatment prevented diet-induced obesity and insulin resistance in animal models
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Research published in Oxidative Medicine and Cellular Longevity (Pickart et al., 2012) confirmed GHK-Cu's role in stimulating collagen synthesis, attracting immune cells to injury sites, and supporting wound healing across multiple tissue types
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