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Other common side effects include diarrhea, constipation, vomiting, abdominal pain, and decreased appetite (which is partly how the medication works)

Quick Tip: Drink a glass of water first thing in the morning to jump-start your skins cellular renewal process

Body Composition Results (12mg Dose, 48 Weeks) Context on lean mass loss: Some lean mass loss (25-30%) is typical with any significant weight loss, including bariatric surgery Lean mass includes muscle, water, bone, and organs, not just muscle The glucagon component may help preserve muscle compared to GLP-1-only drugs Resistance training + adequate protein (1.0-1.2g/kg daily) can minimize muscle loss Visceral Fat Reduction Retatrutide also led to large reductions in visceral adipose tissue (VAT), the fat surrounding internal organs that's linked to metabolic disease

If you choose forearm injection, target the outer surface between your wrist and elbow, avoiding visible veins and areas with visible bruising