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Here we provide an overview of irAEs for current ICIs and their management, aligned with the NCCN Guidelines: Management of ImmunotherapyRelated Toxicities (Version 1.2025), and the Society for Immunotherapy of Cancer (SITC) clinical practice guideline on ICIrelated adverse events (Rapid Update v1.2, published 2024)

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Inositol (50mg): Inositol contributes to fat metabolism and cellular health by supporting insulin function and lipid transfer across cell membranes

(2018), BPC-157 exhibits cell-protective properties by safeguarding the integrity of the GI mucosa [8]