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The trial randomised 2,339 adults with obesity (or overweight with a weight-related comorbidity) and without type 2 diabetes to retatrutide 4mg, 9mg, or 12mg weekly (titrated upward from 2mg in four-weekly steps) or placebo
At the highest tested dose of 12mg administered once weekly, participants lost an average of 24.2% of their body weight
Instead of leading to better health and more satisfaction, our obsessive cycle of dieting and being skinny is leading to disordered eating and the abuse of prescription medication
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