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Not necessarily, but your doctor may reduce the dose of blood pressure medications as semaglutide takes effect and your weight decreases
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Semaglutide has been shown to lead to sustained weight loss of about 15% 1
SGLT2 inhibitors were chosen as the comparator given they are guideline-recommended second-line glucose-lowering medication and share similar cardiovascular benefits with GLP-1RA, which helps reduce confounding by indication
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