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In rare cases, people with certain types of cancer can also develop acanthosis nigricans
Furthermore, testosterone molecules themselves can be damaged by free radicals once they are in the bloodstream
prescription meds and some OTC meds (Tylenol) UV radiation, medical X-rays, chemotherapy, electromagnetic fields Alcohol use and abuse Unrelieved stress, poor sleep, and lack of exercise or too strenuous exercise which can produce too many free radicals Poor diet, especially one thats low in vitamins, minerals or antioxidants The natural aging process, which drops cellular glutathione production on average 10% per decade In short, when your body's demand for glutathione outpaces its supply, oxidative stress ramps up and that's when problems start