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Biological analyses were performed on PBMCs, assessing mitochondrial enzymology (citrate synthase and ETC complexes) and mitochondrial respiration using Seahorse XFe96 with the mitochondrial oxidative stress test
This damage can result in mutations within oncogenes such as RAS and MYC, as well as tumor suppressor genes like p53 and PTEN, thereby fostering genomic instability and malignant transformation [31, 32]
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