290 Phase 3 clinical trials CheckMate 7FL and KEYNOTE-756 have reported improved pCR rates with neoadjuvant chemotherapy and ICI treatment
Sleep optimization strategies: Target 7-9 hours in a dark, cool room (65-68F) Avoid blue light 90 minutes before bed Consistent sleep/wake schedule, including weekends Limit alcohol it severely disrupts REM sleep and glucose regulation Cortisol and GLP-1 Resistance Chronic stress elevates cortisol, which has a bidirectional negative relationship with GLP-1
Pastoris, O., Dossena, M., Foppa, P., Catapano, M., Arbustini, E., Bellini, O., Dal Bello, B., Minzioni, G., Ceriana, P., and Barzaghi, N
Phytochemistry 71, 853859