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Prolonged IGF-1 elevation may interfere with insulin signaling pathways, resulting in glucose metabolism disruption and increased diabetes risk. Clemmons, The Journal of Clinical Endocrinology & Metabolism Cell Overproliferation and Cancer Concerns IGF-1 promotes cell growth and replication , which is great for musclebut not ideal in individuals with: A history of cancer A family history of hormone-sensitive tumors Undiagnosed growths or cysts IGF-1 is considered mitogenic , meaning it encourages cell division
POR, cytochrome P450 oxidoreductase
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Your dosage may still be building up Most people start at a low dose (like 0.25mg for Ozempic) and gradually increase over several weeks or months
