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Moreover, histological examinations of paw edema revealed that ASE (given by gavage at 100 mg/kg BW for 10 days) ameliorate inflammation and oxidative stress status as outlined by anti-edematous, antioxidant and inflammatory biomarkers

They are not a replacement for emergency care, crisis support, or treatment for severe psychiatric conditions, but they can be considered as an adjunct when someone is medically stable and looking for more complete brain and mood support

Each of these conditions tends to improve as weight comes down, which is a big part of the clinical case for treating them together

Summary: High vitamin B12 levels rarely cause direct symptoms