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Paul Coates, former director of the Office of Dietary Supplements at the National Institutes of Health, reviewed many of the scientific studies on Protandim, including the one demonstrating a 7% increase in lifespan for male mice, and said he found them to be largely well designed, if small in scope

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Clinical studies have confirmed significant alterations in both the gut microbiota composition and BAs profiles in SZ patients (77), highlighting a potential correlation between BAs dysregulation and the disorder