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Retatrutide (GLP-3): The Triple Agonist Peptide By Emerald Peptides Research Team | Reviewed for accuracy by our analytical chemistry team Published: November 20, 2025 Retatrutide (GLP-3): The Triple Agonist Peptide A Research Overview Retatrutide is a synthetic triple hormone receptor agonist that simultaneously targets the GLP-1, GIP, and glucagon receptors currently the most advanced compound in the incretin research class