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GLP-1 therapy addresses not only weight reduction but also helps regulate blood sugar patterns, which becomes increasingly relevant as insulin sensitivity naturally declines after age 30
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Moreover, canagliflozin hindered the transition from the G1 to S phase in the cell cycle and downregulated the expression levels of key cell cycle regulators, including cyclin D1, cyclin D3, cyclin E1, cyclin E2, and E2F1
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