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In old rats with OVX-induced osteoporosis, exendin-4 decreased the concentration of C-terminal cross-linked telopeptides of type I collagen (CTX-1) and the urinary deoxypyridinoline (DPD)/creatinine ratio (31)
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In mouse models of pancreatic and lung cancer, retatrutide reduced tumor engraftment rates and suppressed tumor growth through immune reprogramming mechanisms
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