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This growing market reflects the urgent need for affordable alternatives to expensive GLP-1 meds that can cost thousands of dollars each month
Interestingly, tirzepatide, a dual-acting GIP/GLP-1 receptor agonist that is now clinically approved for both obesity and T2D, was designed with an amino acid sequence closely resembling that of native GIP, resulting in strong preference for GIPR binding over the GLP-1R
Genetic predisposition to MS through expression of specific human leukocyte antigen (HLA) alleles associated both with antigen presentation and other autoimmune diseases is also widely documented (71)
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