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This may limit the therapeutic potential of ADI as an arginine depleting agent for cancer treatment
Adults with a BMI of 30 kg/m or higher-or at least 27 kg/m with weight-related comorbidities-who have not succeeded with lifestyle changes alone and who do not have contraindications such as heart disease, uncontrolled hypertension, glaucoma, hyperthyroidism, pregnancy, or a history of drug abuse
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