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The combination is particularly relevant in experimental models dedicated to the study of connective tissues, vascular models, cutaneous systems, muscular paradigms, and preclinical analyses aimed at understanding mechanisms of cytoprotection and regeneration
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Laboratory research demonstrates that FOXO4-DRI's selectivity stems from exploiting fundamental differences between senescent and healthy cell biology, particularly the paradoxical state where senescent cells are primed for apoptosis but protected by specific survival mechanisms
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