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However, this slower digestion can disrupt your guts rhythm, leading to digestive issues like diarrhea, bloating, and nausea

Optogenetic stimulation of PVH-projecting GABA LH neurons increases inhibitory post-synaptic current (IPSC) in PVH neurons, leading to increased feeding, while disruption of GABA receptors in the PVH reduced feeding [89]

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If a dose is missed, skip it and take the subsequent amount the next day