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The endogenous antioxidant enzymes and other antioxidant nutrients are responsible for combating the burden, but are limited in this capacity when the burden is becomes too heavy
The generation of ROS can be activated by endogenous factors, such as the mitochondrial electron transport chain (ETC), NADPH oxidases (NOX), lipoxygenases (LOX), cytochrome P450, and xanthine oxidase (XO), or by exogenous causes such as pollutants, chemicals/drugs, radiation and heavy metals (Moussa et al., 2019)
Gonzalez-Quintela A., Mella C., Perez L
3 AhmadiM.BekeschusS.WeltmannK.von WoedtkeT.WendeK
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