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Lets walk through the chain of events in this graphic to help you understand whats really going on with Hashimotos

doi:10.1183/09031936.05.00003705 [22] Fowdar K, Chen H, He Z, et al

Notably, the Gprc5a -ko mouse lung cancer model exhibits two significant characteristics: the spontaneous development of lung tumors and a persistent state of inflammation

Our results show that glutathione efflux from hepatocytes results in high local concentrations of both glutathione and cysteine in liver sinusoids, which transforms the nanoparticle surface chemistry, reduces its affinity to serum protein and significantly alters its blood retention, targeting and clearance