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Baseline measurements were taken after an initial 5 min of incubation with coelenterazine-h or NanoGlo-containing PBS after which cells were then treated with either vehicle (PBS) or respective ligands

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Subsequently, H 2 O 2 formation as a by-product of epithelial growth factor (EGF) induces the Akt (Protein kinase) and P70S6K1 (Ribosomal protein S6 kinase beta-1) signalling that are involve in protein synthesis during human ovarian cancer cells