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possibly related to NO-mediated vasodilation

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Despite lacking MC-R binding motifs, KPV exhibits significant anti-inflammatory effects, making it a promising candidate for research into peptide compounds in immune-mediated inflammatory diseases like skin conditions, bowel diseases, asthma, and arthritis

Kidney Overload : It is unusual for a persons kidney function to be affected by a high protein intakeas with collagen supplements, because of pre-existing kidney issues