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The activation of PPAR- promotes adipogenesis induces ectopic adipocyte formation in non-adipose tissues [68]
doi: 10.1016/j.freeradbiomed.2013.07.036 190 MaesMMihaylovaIKuberaMUytterhoevenMVrydagsNBosmansE
however, those with G6PD deficiency may exhibit more severe side effects than those with in-tact G6PD as a result of a decreased threshold for processing ROS in the liver
These are consistent with the mechanism of action slowing gastric emptying affects digestion, and central appetite suppression can cause nausea, particularly during the early stages of treatment and dose escalation
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