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Their fibroblasts are still responsive, and the collagen remodeling signal from GHK-Cu generates new fiber at a rate that shows clearly within the 12-week window
Similar concept to peptides (delivering growth signals) but different mechanism (autologous growth factors from patient's blood)
TB-500 has also been studied in models of critical limb ischemia, with research indicating that it may interact with Notch and NF-B pathways
Overall, 59% of patients reported a meaningful response measured as either a GRA-based improvement or 50% reduction in ICSI score
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