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At PDA Week 2025, Lorraine O'Shea from Eli Lilly's Kinsale team presented on plug flow reactor technology adapted for continuous peptide coupling reactions, describing how the approach eliminates the need for large-volume batch reactors while enabling scalable production

The significance of our work lies in expanding the understanding of the multifunctional nature of USP2 and its implications across an array of pathophysiological circumstances

hs-CRP, high-sensitivity C-reactive protein

But tirzepatide has already proven itself across multiple large-scale trials involving tens of thousands of participants, with established dosing protocols, known side effect patterns, and widespread clinical use