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Risk groups: Conditions when Phentermine and Semaglutide are not recommended together or even separately are type-2 diabetes, heart disease, kidney or gallbladder issues, pancreatitis, glaucoma, hyperthyroidism, and medullary thyroid cancer or multiple endocrine neoplasia

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Data availability The authors declare that all data supporting the findings of this study are available within the article and the Supplementary Information