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Prescription rate of GLP-1s based on diagnosis Source: Piaopiao, L et al JAMA Network Open October 31, 2025 Research published in JAMA Network Open evaluated trends in prescribing of GLP-1 agents from 2010 through the end of 2024 using the Cosmos data warehouse, which has at least some medical records for 300 million Americans

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New trials emphasize consistent fat loss across weeks, with some patients shedding as much as 24% of body weight within a year

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