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Singh added that results from the ongoing FOCUS studya long-term ophthalmic endpoint trial evaluating semaglutide versus placebo in patients with type 2 diabeteswill be critical in clarifying the long-term retinal safety profile of GLP-1 therapies

Mouse and human studies have found that intranasal insulin reduces central nervous system inflammation and improves cognition by reducing proinflammatory cytokine levels and oxidative stress, and boosting antioxidant levels and mitochondrial functioning

The GLP-1 agonist exendin-4 attenuates self-administration of sweetened fat on fixed and progressive ratio schedules of reinforcement in rats

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