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reinstated December 2025 (status: monitor closely) States that restrict coverage: Michigan restricted to BMI 40 (morbid obesity) with strict prior authorization criteria

Mechanical Complications Excess body weight creates abnormal mechanical loading on weight-bearing joints

(14) It is hypothesized that GHK-Cu may influence various biochemical pathways and molecular markers related to inflammation and oxidative stress, although the specific mechanisms remain somewhat uncertain

This makes them ideal locations for a shot that needs to be injected just under the skin, as opposed to an intramuscular injection that needs to go past layers of skin and fat to get deep into a muscle