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To facilitate absorption by the human body and reduce irritation, it is necessary to dilute it with a special diluent before injection

First identified in the 1990s during research into gastric mucosal protection, BPC-157 has since been studied in numerous animal models for its seemingly broad healing properties

As a vital constituent of antigen-presenting cells (APCs), macrophage possesses two exact opposite-in-function phenotypes, M1 and M2, the former polarized by lipopolysaccharide (LPS), producing pro-inflammatory cytokines such as IL-1, IL-6, IL-12, IL-23, and TNF-, the latter polarized by Th2 cytokines, producing anti-inflammatory cytokines such as IL-10 and TGF- [20]

Certificates of Analysis for Klow list this component under its full name, thymosin beta-4, rather than the TB-500 shorthand