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In a rat model of retinal degeneration, prenatal and postnatal administration of Epitalon preserved retinal structure and doubled electrophysiological retinal activity [55]
Higher doses reached that plateau later in the trial. In a 112-week step-down trial, participants maintained 21.9% loss on the top dose, 16.6% after stepping down to 5 mg, and 9.9% on placebo
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