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However, despite being the mainstay of CRC chemotherapy treatment, the primary anti-tumour mechanismsand more importantly, mechanisms facilitating 5FU resistance and persistenceremain poorly defined
New England Journal of Medicine (2025) 3
Brain 136 , 20982108 (2013)
Therefore, maintenance of glutathione homeostasis appears as a critical effector mechanism for OPC protection against NADPH depletion and preservation of the regenerative potential of the injured white matter
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