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6 Encouragingly, some evidence suggests that physical function can improve with GLP-1 therapy despite some lean mass reduction, likely due to the significant fat loss and overall improvement in body composition
The study showed that orforglipron led to significant weight changes in participants, especially at the highest dose
This approach has gained popularity in online communities, particularly among people who are sensitive to GI side effects or who want to ease into treatment as gradually as possible
Adults with obesity have a body mass index (BMI) of over 30 or higher
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