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3 Because postprandial hyperglycemia affects A1C to a greater degree than fasting hyperglycemia, the closer a patient is to the A1C goal, GLP-1 receptor agonists provide a viable treatment option to target postprandial glucose excursions due to their glucose-dependent effects on insulin secretion
Peptides are largely broken down by digestive enzymes in the gastrointestinal tract before they can be absorbed intact
doi: 10.1210/jcem.87.3.8345 199 TruongMCookMRPinchotSNKunnimalaiyaanMChenH
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