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Less volume typically means less injection site reaction, less post-injection discomfort, and faster absorption

1 The GIPR association was specific to tirzepatide, Eli Lilly's dual GLP-1 and GIP receptor agonist sold as Mounjaro and Zepbound, with carriers of that variant found to be 83% more likely to experience vomiting than non-carriers

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The good news is that most sleep-related issues resolve as treatment continues, and many patients ultimately sleep better due to reduced sleep apnea and nighttime reflux as weight decreases