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In another adjuvant breast cancer trial (the ECOG-1178 trial), hot flashes were reported in 19% of women who received 2 years of tamoxifen compared with 8% of women who received placebo following a mastectomy
In addition, they show antifungal activity against Aspergillus flavus , A niger , and A fumigatus , and yeasts such as Rhodotorula mucilaginous , Candida krusi , C glabrata , and C albicans (100, 125)
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Recommendation: Aim for 310-420 mg daily, depending on age and gender
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