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However, I find that on an empty stomach the 500 mg tablet causes some stomach discomfort which at times has actually precipitated Atrial Fibrillation, so I have been taking it with meals

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Standard semaglutide titration The typical schedule starts at 0.25mg weekly for the first 4 weeks, then increases to 0.5mg for weeks 5 through 8, then 1mg, 1.7mg, and eventually 2.4mg (the maximum approved dose for weight management)

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