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SUSTAIN 4 and SUSTAIN FORTE were only powered to detect differences in A1C from baseline to Week 30 and Week 40, respectively

Gut Microbiome Effects Emerging research suggests that GLP-1 receptor agonists may favorably alter the gut microbiome, reducing gut permeability (leaky gut) and the translocation of bacterial endotoxins that trigger systemic inflammation

It plays a crucial role in the development of male reproductive tissues, secondary sexual characteristics (such as muscle mass, bone density, and body hair), and overall well-being