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Much of the discussion surrounding it is based on laboratory and animal research rather than large, peer-reviewed human trials
While there is some evidence for Nrf2 activation in neurodegeneration, it appears to be relatively mild and clearly insufficient to prevent neuronal dysfunction ( The above mentioned studies in cancer cells provide empirical in vitro support for the anti-ferroptotic action of Nrf2
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Role of ferroptosis in T2DM Ferroptosis is a regulated form of cell death driven by iron-dependent lipid peroxidation
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